The TradeEdgeMiami Heat suffered more than one loss Wednesday in their NBA play-in tournament game against the Philadelphia 76ers.

Star forward Jimmy Butler sprained the MCL in his right knee early in the 105-104 defeat and will miss Friday's play-in game against the Chicago Bulls for the No. 8 seed in the Eastern Conference. His status beyond that has not been determined, and there is hope he could be day-to-day if the Heat win.

The incident came at the end of the first quarter when Butler was fouled by the Sixers' Kelly Oubre Jr. on a layup attempt. He remained down on the court for an extended period of time before taking his free throws and heading to the bench.

"I fell, he landed and my knee just didn't do well, I guess," Butler said after the game. "I don't know. It's not a good feeling, I can tell you that."

Butler eventually returned to the game, but was just 5-for-18 from the field in finishing with 19 points. He had an MRI on his knee Thursday.

All things Heat: Latest Miami Heat news, schedule, roster, stats, injury updates and more.

The Bulls-Heat winner will travel to face the top-seeded Boston Celtics in Game 1 of a first-round series Sunday.

"We just need to get one and then we'll worry about the next one," Butler said.

Last season, Miami advanced from the play-in tournament all the way to the NBA Finals before eventually losing to the Denver Nuggets.